Clinical Observation of Huatanjieyu Granule in the Treatment of Post-stroke Depression

更新时间:2023-05-28

【摘要】[Objectives] To observe the clinical effect of Huatanjieyu granule on patients with post-stroke depression. [Methods] Total 76 patients with confirmed post-stroke depression were randomly divided into two groups(treatment group and control group) according to the double-blind principle. The treatment group(38 cases) was treated with Huatanjieyu granule combined with escitalopram, and the control group(38 cases) was treated with escitalopram alone. The course of treatment was 6 weeks. Through clinical efficacy, Hamilton Depression Scale(HAMD) and Treatment Emergent Symptom Scale(TESS) scores were compared, and blood, liver function, renal function and electrocardiogram were examined. [Results] The scores of HAMD and TESS in patients with post-stroke depression were significantly decreased by Huatanjieyu granule, and there were no obvious side effects. The total effective rate was 92.1% in the treatment group and 76.3% in the control group. There was significant difference between the two groups(P<0.01). [Conclusions] Huatanjieyu granule was effective in the treatment of post-stroke depression with little side effects and was easy to be accepted by patients.

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